Thursday, March 25, 2010

Men who never sleeps !!

Have you ever imagined a life where you wanna sleep ,but you can't !! well, that would be the worst nightmare for anyone.A rare disease called "Fatal Familial Insomnia" can make this nightmare becoming a true story.it is a rare curse that affects about 40 families around the world. It is caused by prion diseases (mutated proteins) which can affect both humans and animals.Here is one true story of Fatal Familial Insomnia.


Shortly after his 40th birthday in 1991, Michael Corke, a music teacher from Chicago, began having trouble sleeping. In the following weeks, the insomnia grew worse and his health rapidly deteriorated. Eventually he couldn’t sleep at all.The doctors were baffled but could do nothing for him. Michael was physically and mentally exhausted, and wanted nothing more than to be able to fall asleep. But his brain wouldn’t let him.He soon started to look like an old man from a fit and healthy individual he was just months earlier. doctors diagnosed him with an extremely rare genetic disorder called "Fatal Familial Insomnia" .

Michael Corke died in hospital after six months from a complete lack of sleep.

Symptoms of Fatal Familial Insomnia:

  • Severe insomnia, worsening panic attacks and hallucinations, lasting for five months.
  • Complete insomnia and rapid weight loss, lasting for three months.
  • Dementia and unresponsiveness, lasting for six months. FFI is eventually fatal.

Causes of Fatal Familial Insomnia:

Fatal Familial Insomnia is caused by a dual mutation in a gene that codes for proteins. The tell-tale sign of prion diseases is an insoluble protein that causes plaque to develop in the thalamus. This is the region of the brain responsible for the regulation of sleep, as well as sensory and motor systems.

As the plaque "eats away" at the brain, the sufferer loses the ability to shut down at night. This manifests in the form of insomnia. The resulting symptoms of FFI are caused by the complete lack of REM and NREM sleep, proving that sleep is vital to everyone.

Treatments for Fatal Familial Insomnia:

Currently there is no treatment for this , however sleeping peels only worsen the problem.

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